Yu-Gi-Oh! Episode 43: Big 5`s Trap: Duel Monsters Quest
Episode 43 of 224 of Yu-Gi-Oh!, aired February 20, 2001, 25 minutes. Available with English subtitles and dub where released.
Episode summary
The traitorous board of directors of Kaiba Corporation trap Seto Kaiba inside his own virtual reality game. Mokuba recruits Yugi and Joey to free him from this ultimate game, where the cost of losing is death.